⭐ CHEMOTHERAPEUTIC AGENTSπŸ“Œ POINTS TO PONDERπŸ”ΉPin Cushion Effect- One charged end of chlorhexidine (CHX) molecule binding to the tooth surface and the other remaining available to interact with bacterial membrane as microorganism approaches the tooth surface as pin-cushion effect.πŸ”ΉSubstantivity of CHX is around 12 hrs.πŸ”ΉSubstantivity of Triclosan is around 5 hrs.πŸ”ΉSubstantivity of Cetylpyridium is around 3-5 hrs.πŸ”ΉChemotherapeutic agents used as premedication in periodontal surgery are anxiolytics, antibiotics,antiseptics and NSAIDs.πŸ”ΉThree groups of antimicrobials which interfere with food absorption are tetracyclines, quinolones and azithromycin.

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