🔹Hypertrophy is an increase in the size of cells causing the increase in the size of the tissues.
🔹Hyperplasia is an increase in number of cells in a tissue thus, contributing to an overall increase in the size.Â
🔹Gingival hyperplasia is caused mainly by an increase in the number of local cellular elements and intercellular fibers.
🔹The clinical features of phenytoin-induced hyperplasia are different from that of idiopathic fibrous hyperplasia.
🔹The administration of phenytoin often leads to overgrowth of the papillae, leaving the attached gingiva whereas in idiopathic fibrous hyperplasia there is involvement of all marginal, interdental and attached gingiva.
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