TOPIC : POSITRON EMISSION TOMOGRAPHY AND FUSION IMAGING🌟 IMPORTANT POINTS TO REMEMBER🔹Principle Of PET: It relies on positron-emitting radionuclides generated in cyclotrons. FDG is a glucose analogue that enters the cell using the same uptake mechanism as normal glucose. Within the cell, FDG is phosphorylated by the enzyme hexokinase to 2-deoxyglucose-6-phosphate.🔹Annihilation Radiation: As a positron is emitted with the tissue, it meets a free electron and mutual annihilation occurs resulting in 551 keV photons emitted 180° to each other. This is called annihilation radiation.
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