📌 POINTS TO PONDER 

🔹Wickham striae – Interlacing white lines are the hallmark  of Reticular oral lichen planus. 

🔹Nikolsky’s sign is the hallmark of Pemphigus vulgaris. 

🔹Target or iris lesions with central clearing are the hallmark of erythema multiforme.

🔹Pemphigus vulgaris lesions demonstrate a characteristic intraepithelial clefting or vesiculation above the basal cell layer with a characteristic “tombstone” appearance.

🔹Keratotic lesions: These are small-raised, round white papules of pinhead size with a flattened surface and usually present on the attached gingiva.

🔹Vesiculobullous lesions: These raised, fluid-filled lesions are uncommon and short-lived on the gingiva. They quickly rupture and leave ulcerations.

🔹Crohn’s disease, also termed as regional enteritis or granulomatous enteritis, is a chronic granulomatous, inflammatory disease characteristically involves the  gastrointestinal tract, particularly the terminal ileum.

🔹Osteosarcoma is composed of malignant stromal cells that form osteoid or primitive bone, formation of bony trabeculae results in a sunray appearance in a direction perpendicular to the outer surface called as “sunburst” appearance.

📌 VIVA VOCE 

Q1. In which conditions gingival red lesion is seen? 

Ans. Desquamative gingivitis; Erythroplasia; Hemangiomas; Orofacial granulomatosis; Crohn’s diseases; Sarcoidosis; Wegener’s granulomatosis and Kaposi’s sarcoma. 

Q2. What is the configuration of rete ridges in Lichen planus? 

Ans. In Lichen planus saw tooth configuration of rete ridges are observed. 

Q3. In which mucocutaneous disorders Nikolsky sign is seen? 

Ans. Pemphigus vulgaris. 

Q4. Which autoantibodies are seen in Pemphigus vulgaris? 

Ans. Serum Ig G autoantibodies against Desmoglein (Dsg1) and Desmoglein (Dsg3) are seen in Pemphigus vulgaris. 

Q5. In which chronic granulomatous disease lip swelling is common? 

Ans. Lip swelling is common in Orofacial granulomatous. 

Q6. Who coined the term “chronic desquamative gingivitis”? 

Ans. Prinz in 1932 

Q7. What are the clinical presentations of systemic lupus erythematosus? 

Ans. Three types: Discoid, erythematous and ulcerations. 

Q8. What are the sources of ameloblastoma origin? 

Ans. Dental lamina rests, epithelial rests of Malassez, reduced enamel epithelium and cystic epithelial lining. 

Q9. What are the common symptoms of Orofacial granulomatosis? 

Ans. Hypertrophy and swelling of lips, gingival swelling, cobblestone appearance of buccal mucosa and palate, and deep ulcers. 

Q10. What are the treatment modalities for lichen planus? 

Ans. Steroids, antifungals, topical and systemic retinoids and cyclosporine.