Cell Injury and Cellular Adaptations
Nuclear Changes in Irreversible Cell Injury Pyknosis → Karyorrhexis → Karyolysis Pyknosis Definition: Nuclear shrinkage with increased basophilia. Look: Small, dark, dense nucleus. Exam tip: First visible step in nuclear damage. Karyorrhexis Definition: Fragmentation of the pyknotic nucleus. Look: Multiple dark nuclear fragments. Exam tip: Seen in both necrosis and apoptosis. Karyolysis Definition: Fading and […]
